IRT for CRC
  • Developing an Integrated Risk Prediction Tool for Colorectal Cancer
  • Cohort used for the study
  • Clinical risk factors
    • Creating the clinical dataframe
    • Creating the clinical risk model
    • Analyzing the results
  • Polygenic risk scores
    • PRSice
    • Preparing to use PRSice
    • Obtaining polygenic risk scores
    • Analyzing the results
    • Plink2
  • Integrated risk score
    • Obtaining integrated risk scores
    • Analyzing the results
  • Working with real patient data
    • Genetic data from Tempus Labs
      • Preparing the data and obtaining polygenic risk scores
      • Interpreting the scores
    • Clinical data from Gastroenterology Atlanta
      • Obtaining integrated scores and understanding the results
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  1. Working with real patient data

Genetic data from Tempus Labs

The micro-array genotyped data for 15 samples was deposited by Tempus Labs in an AWS bucket. The sequencing was done using Illumina technologies.

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Last updated 1 year ago